Strategi Pencegahan Influenza Terhadap Resistensi dan Efektivitas Antiviral : Kajian Literatur

Penulis

  • Aulia Putri Salsabila Universitas Muhammadiyah Bandung
  • Neva Afifah Putri Suharja Universitas Muhammadiyah Bandung
  • Nurul Fadhillah Universitas Muhammadiyah Bandung
  • Wulan Pertiwi Universitas Muhammadiyah Bandung

Kata Kunci:

Influenza, Antivirals, Viral resistance, Therapeutic effectiveness

Abstrak

Influenza is a viral infection that can cause serious complications and spread rapidly. Antivirals such as oseltamivir, zanamivir, peramivir and baloxavir are effective at reducing the duration of illness if given within the first 48 hours. However, viral mutations can lead to resistance to antivirals, decreasing the effectiveness of treatment. This review analyzes antiviral resistance and effectiveness based on a literature review from various sources. Results show that resistance to oseltamivir and amantadine is a major challenge, and antiviral effectiveness is affected by the timing of administration, patient condition, and viral mutations. Several strategies, including antiviral combinations, new drug development, herbal plants, and vaccination, were developed to overcome resistance, but none have been fully effective. Monitoring viral resistance and developing adaptive treatment strategies are needed to improve influenza control.

##submission.downloads##

Diterbitkan

2025-12-31

Cara Mengutip

Salsabila, A. P., Suharja, N. A. P. ., Fadhillah, N. ., & Pertiwi, W. . (2025). Strategi Pencegahan Influenza Terhadap Resistensi dan Efektivitas Antiviral : Kajian Literatur. Jurnal Biodiversitas Dan Bioteknologi, 2(2), 37–45. Diambil dari https://ejournal.umbandung.ac.id/index.php/biodiverse/article/view/663
                                                                  ADOConnection.CacheExecute(3600, SELECT  				o.submission_id,  				MAX(s.context_id) AS journal_id,  				MAX(i.date_published) AS i_pub,  				MAX(p.date_publishe..., Array[2]) % line  132, file: DAO.inc.php
                                                               DAO.retrieveCached(SELECT  				o.submission_id,  				MAX(s.context_id) AS journal_id,  				MAX(i.date_published) AS i_pub,  				MAX(p.date_publishe..., Array[2], 3600) % line   91, file: ArticleSearchDAO.inc.php
                                                            ArticleSearchDAO.getPhraseResults(Object:Journal, Array[1], null, null, , 500, 1) % line  201, file: SubmissionSearch.inc.php
                                                         SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[1], , null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                      SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[4], , null, null, 500, 1) % line  194, file: SubmissionSearch.inc.php
                                                   SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[4], null, null, null, 500, 1) % line  146, file: SubmissionSearch.inc.php
                                                SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line  132, file: SubmissionSearch.inc.php
                                             SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line  263, file: SubmissionSearch.inc.php
                                          SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line   92, file: RecommendBySimilarityPlugin.inc.php
                                       RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line  107, file: HookRegistry.inc.php
                                    HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1256, file: PKPTemplateManager.inc.php
                                 PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line   43, file: 42362804174f266c598cdb32c3208fc745b92101^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
                              content_68d10543495f98_06823047(Object:Smarty_Internal_Template) % line  123, file: smarty_template_resource_base.php
                           Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line  114, file: smarty_template_compiled.php
                        Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line  216, file: smarty_internal_template.php
                     Smarty_Internal_Template.render(false, 1) % line  232, file: smarty_internal_templatebase.php
                  Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, 42362804174f266c598cdb32c3208fc745b92101, null, 1) % line  134, file: smarty_internal_templatebase.php
               Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, 42362804174f266c598cdb32c3208fc745b92101, null) % line  924, file: PKPTemplateManager.inc.php
            PKPTemplateManager.display(frontend/pages/article.tpl) % line  287, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php